sources

Epitope Mismatch Algorithm

Information about the websites used for the development of HLA-EMMA can be found below.

We have used several articles to locate the polymorphic and solvent-accessible amino acid positions on the different HLA-molecules.

Tools that have been used for the development of HLA-EMMA can be found here.

Websites

The IMGT/HLA Database provides a specialist database for sequences of the human major histocompatibility complex (MHC).

The Protein Data Bank provides information about the 3D shapes of proteins, nucleic acids, and complex assemblies.

pHLA3D / HLA Molecules provides a directory with HLA Class I molecules to exam.

Tools

Source for the prediction of protein secondary structure and relative solvent accessibility. The exposed positions of HLA molecules for class I and class II are defined by two tools.​

Articles

NetSurfP-2.0: Improved prediction of protein structural features by integrated deep learning.

Klausen et al. 2019 Proteins 87

Porter, Pale Ale 4.0: high-accuracy prediction of protein secondary structure and relative solvent accessibility.


Mirabello et al. 2013 Bioinformatics 29