Epitope Mismatch Algorithm
HLA-EMMA was developed at the department of Immunology, LUMC and is a free tool for registered users to compute donor and recipient HLA compatibility at the amino acid level. This tool is only available for Windows OS. Please create a login and download the setup.
HLA-EMMA requires an activation key. To activate your copy of the software, you will be prompted for a licence. Please send an email to info@HLA-EMMA.com with the generated key to obtain a licence to activate your copy of HLA-EMMA.
HLA-EMMA is a user-friendly tool to define polymorphic solvent accessible amino acid mismatches between recipient and donor. HLA-EMMA generates for each donor HLA allele a total number of amino acid mismatches and number of solvent accessible amino acid mismatches.
With the batch option, an unlimited number of donor and recipient pairs can be analysed at once.
The batch input format is a Microsoft Excel file and the output file of HLA-EMMA is a XML file which you can easily import in Microsoft Excel for further analyses.